Podcast

PODCAST | Biosecurity in the Era of Science Fiction: AIxBio and Project Paraphrase with Bruce Wittmann

Shane Reader
Headshot of Bruce Whitman

It seems like every week there’s another headline about a breakthrough in AIxBio: the intersection of artificial intelligence and biological science. AI is being applied to accomplish feats that sound like science fiction. It’s being used to control laboratories, connect with our brains, and even create new viruses. But is there a lesson to be learned in science fiction? In this episode, host Shane Reader calls up Bruce Wittmann, Principal Applied Scientist at Microsoft, to discuss how AI-powered biological tools work, the ways they’re being applied in biological research, and what he did when he discovered a biological “zero day” vulnerability that could have potentially empowered bad actors.

Read more about Project Paraphrase here.

Guest

Bruce Wittmann, Ph.D.
Principal Applied Scientist, Microsoft

Host & Producer

Shane Reader, M.A., Ph.D.
2025 - 2026 AAAS Congressional Fellow, United States Senate
2024 - 2025 AAAS Executive Fellow, Countering Weapons of Mass Destruction, Department of Homeland Security

Disclaimer

This blog does not necessarily reflect the views of AAAS, its Council, Board of Directors, officers, or members. AAAS is not responsible for the accuracy of this material. AAAS has made this material available as a public service, but this does not constitute endorsement by the association.

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Authors

Shane Reader

Reader, Shane: Fellowship 2024-2025 Reader, Shane: Fellowship 2025-2026

Shane Reader, M.A. Ph.D., is a health policy scientist committed to integrating evidence-based policy into the healthcare system to improve outcomes, reduce costs, and prepare for the next pandemic. He earned his M.A. in Psychology at Texas A&M University-Corpus Christi and a Ph.D. in Health Policy at the University of Texas Health Science Center. Informed by both peer-reviewed science and hands-on policymaking experience in the Executive Branch, Shane drives solutions in healthcare, biosecurity, and emerging technology. With a record of cross-sector collaboration and coalition-building, he brings a practical, data-driven approach to policy development.  In his preceding fellowship, Dr. Reader advanced biodefense interests at the National Security Council and White House Office of Science and Technology Policy.